What is a common diagnostic challenge in feline oncology?

Differentiating between benign and malignant lesions is a significant diagnostic challenge in feline oncology due to several factors inherent to feline tumors. Cats often present with neoplasms that may not exhibit typical behavior or characteristics that are easily classified. The biological behavior of some tumors can be quite deceptive; for instance, certain benign tumors may mimic malignant ones in imaging studies or histopathological evaluations. Additionally, some malignant tumors can have histological grades that are indistinguishable from benign lesions, complicating the prognostic assessment.

Feline patients may also have a varied presentation of tumors, and the limited availability of some advanced imaging techniques can restrict the ability to fully evaluate the tumor's nature. The overlapping clinical features of certain neoplasms further contribute to the difficulty in making a definitive diagnosis. Accurate differentiation is crucial since the treatment approach and prognosis can significantly differ based on whether a tumor is benign or malignant. This challenge emphasizes the need for careful histopathological examination, potentially incorporating immunohistochemistry and other diagnostic modalities to support accurate classification and treatment planning.